Cognitive Dysfunction and Gait Abnormalities in CKD

Clin J Am Soc Nephrol.
May 18, 2021

The gait phenotype was associated with poorer function in a number of cognitive domains among older adults with CKD, and was associated with incident mild cognitive impairment independent of eGFR.

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Lower Extremity Nerve Injury in Childbirth

MCN
May 18, 2021

Nurses can advocate for patients by promoting multidisciplinary and patient education about LENI and ensuring that their practice setting has implemented appropriate assessment, education, and documentation strategies to detect and address it.

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Telehealth Privacy and Security Tips

Skyscape
May 18, 2021

Buzz, a HIPAA-complaint platform enables providers to conduct secure video conferences or calls with patients quickly, easily & seamlessly.

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Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke

NEJM
May 17, 2021

Among participants with AF who had undergone cardiac surgery, most of whom continued to receive ongoing antithrombotic therapy, the risk of ischemic stroke or systemic embolism was lower with concomitant left atrial appendage occlusion performed during the surgery than without it.

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Intraoperative irradiation for early breast cancer (ELIOT)

The Lancet
May 17, 2021

The long-term results of this trial confirmed the higher rate of IBTR in the ELIOT group than in the WBI group, without any differences in overall survival. ELIOT should be offered to selected patients at low-risk of IBTR.

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Genetic basis of lacunar stroke

The Lancet
May 14, 2021

Lacunar stroke has a substantial heritable component, with 12 loci now identified that could represent future treatment targets.

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Pelvic organ prolapse after 3 modes of hysterectomy

Am J Obstet Gynecol
May 14, 2021

Prolapse, as an indication for hysterectomy, increases risk for recurrence. Women planning a hysterectomy should be counseled appropriately about the risk of subsequent prolapse.

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Management of simple and retained hemothorax

Am J Surg
May 13, 2021

For traumatic hemothorax, pigtail catheters are conditionally recommend in hemodynamically stable patients. In patients with rHTX, VATS are conditionally recommended rather than attempting thrombolytic therapy and it is recommended that it should be performed early (<=4 days).

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Efficacy of Intravenous Ketamine in Adolescent Treatment-Resistant Depression

Am J Psychiatry
May 13, 2021

In this first randomized placebo-controlled clinical trial of intravenous ketamine in adolescents with depression, the findings suggest that it is well tolerated acutely and has significant short-term (2-week) efficacy in reducing depressive symptoms compared with an active placebo.

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CAPN1 (Calpain1)-Mediated Impairment of Autophagic Flux Contributes to Cerebral Ischemia-Induced Neuronal Damag

Stroke
May 12, 2021

The present study demonstrates for the first time that ischemia-induced CAPN1 activation impairs lysosomal function and suppresses autophagosome formation, which contribute to the accumulation of substrates and aggravate the ischemia-induced neuronal cell damage.

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