Phase II Trial of Costimulation Blockade with Abatacept for Prevention of Acute GVHD

J Clinical Oncology
Jun 11, 2021

The results suggest that abatacept may substantially improve AGVHD-related transplant outcomes, with a particularly beneficial impact on HLA-mismatched HCT.

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Geriatric Clinical Screening Tool for CSI After Ground-level Falls

Emerg Med J.
Jun 11, 2021

Midline tenderness, focal neurological deficit and signs of trauma to the head/face were significant in this older population. The absence of all three variables indicates lower likelihood of CSI for patients>=65.

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Telehealth Privacy and Security Tips

Skyscape
Jun 13, 2021

Buzz, a HIPAA-complaint platform enables providers to conduct secure video conferences or calls with patients quickly, easily & seamlessly.

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Risk of Subsequent Fractures in Postmenopausal Women After Nontraumatic vs Traumatic Fractures

JAMA
Jun 10, 2021

In this cohort study, among postmenopausal women older than 50 years, fracture was associated with a greater risk of subsequent fracture regardless of whether the fracture was traumatic or nontraumatic.

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Treatment of Infantile-Onset Spinal Muscular Atrophy with Nusinersen

The Lancet
Jun 10, 2021

The findings are consistent with other trials of nusinersen and show improved survival and attainment of motor milestones over 3 years in patients with infantile-onset spinal muscular atrophy, with a favourable safety profile.

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Parathyroid Identification During Thyroid and Parathyroid Operations

Am J Surg
Jun 09, 2021

The aim of this study was to develop a low-cost prototype near-infrared fluorescence device that enables contrast-free, real time, high-resolution intraoperative visualization of normal and pathological parathyroid glands (PGs) by imaging their autofluorescence (AF).

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Sustainability of Neutralising Antibodies Induced by Bivalent or Quadrivalent HPV Vaccines

The Lancet
Jun 09, 2021

Significant differences in the immunogenicity of the two vaccines are in line with the differences in their cross-protective efficacy. Protective HPV vaccine-induced antibody titres can be detected up to 12 years after vaccination.

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Bimodal Expression of Rhoh During Myelomonocytic Differentiation

eJHaem
Jun 08, 2021

The results indicate that RHOH induction is a driver of terminal differentiation and might represent a means of effecting AML differentiation therapy.

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Impact of Obstetric Emergency High-Fidelity Simulation on Maternity Nurses' Self-Efficacy in the Rural Hospital Setting

MCN
Jun 08, 2021

Health care institutions should consider investing in high-fidelity simulation education or partnering with academic institutions that have simulation centers to promote maternity nurses' self-efficacy that can potentially translate into improved clinical skills and improved patient outcomes.

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Association between Obstructive Sleep Apnea and Exfoliation Syndrome

Ophthalmology Glaucoma
Jun 07, 2021

Patients with OSA may be at an increased risk of XFS compared with patients without OSA, particularly in patients with a history of HTN.

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