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Read MoreAdjunctive Psychotherapy for Bipolar Disorder
This study suggests that outpatients with bipolar disorder receiving pharmacotherapy should also be offered psychosocial treatments that emphasize illness management strategies and enhance coping skills; delivering these components in family or group format may be especially advantageous.
Read MoreA Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis
For the treatment of appendicitis, antibiotics were noninferior to appendectomy on the basis of results of a standard health-status measure. In the antibiotics group, nearly 3 in 10 participants had undergone appendectomy by 90 days.
Read MoreImpact of a Weekly Glucagon-Like Peptide 1 Receptor Agonist, Albiglutide, on Glycemic Control and on Reducing Prandial Insulin Use in Type 2 Diabetes Inadequately Controlled on Multiple Insulin Therap
A once-weekly GLP-1RA was able to substitute for prandial insulin in 54% of people, substantially reducing the number of prandial insulin injections; glycemic control improved, with the added benefits of weight loss and less hypoglycemia in the GLP-1RA arm.
Read MoreThe Expected 30-Year Benefits of Early Versus Delayed Primary Prevention of Cardiovascular Disease by Lipid Lowering
Substantial reduction in expected atherosclerotic cardiovascular disease risk in the next 30 years is achievable by intensive lipid lowering in individuals in their 40s and 50s with non-HDL-C >=160 mg/dL.
Read MoreIdentification of Novel Risk Loci and Causal Insights for Sporadic Creutzfeldt-Jakob Disease
The first evidence of statistically robust genetic associations in sporadic human prion disease that implicate intracellular trafficking and sphingolipid metabolism as molecular causal mechanisms.
Read MoreFDA Approves First Treatment for Ebola Virus
FDA approved Inmazeb (atoltivimab, maftivimab, and odesivimab-ebgn), a mixture of three monoclonal antibodies, as the first FDA-approved treatment for Zaire ebolavirus (Ebola virus) infection in adult and pediatric patients.
Read MoreUnderstanding Transient Ischaemic Attack (TIA)
TIA is a complex medical diagnosis with multiple risk factors that may make the management complex and hence difficult for patients to undertake.
Read MoreNebulized Tranexamic Acid for Recurring Hemoptysis in Critically Ill Patients
Tranexamic acid may be considered in the treatment of hemoptysis regardless of the underlying cause. This may be utilized pending further workup and investigation into the underlying source of the bleeding.
Read MoreAKI and Risk of CKD and Hypertension after Pediatric Cardiac Surgery
CKD and hypertension burden in the 4 years after pediatric cardiac surgery is high. Young age at surgery, but not AKI, is associated with their development.
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