Antibiotic Resistance Pattern in Children with UTI

Am J Peds.
Dec 12, 2019

Empirical antibiotic selection should be based on knowledge of the local prevalence of bacterial organism and their antibiotic resistance in a specific area.

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Evidence for Dissociable Linkage of Dimensions of Psychopathology to Brain Structure in Youths

Am J Psychiatry
Dec 12, 2019

Fear symptoms were associated with reduced cortical thickness in most networks, and overall psychopathology was associated with globally reduced gray matter volume across all networks.

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Safety and Effectiveness of Upadacitinib or Adalimumab Plus Methotrexate in Patients with Rheumatoid Arthritis

Ann Rheum Dis
Dec 11, 2019

Patients with an insufficient response to adalimumab or upadacitinib safely achieved clinically meaningful responses after switching to the alternative medication without washout.

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Gastric Bypass Versus Sleeve Gastrectomy in Patients with Type 2 Diabetes (Oseberg)

The Lancet
Dec 11, 2019

Gastric bypass was found to be superior to sleeve gastrectomy for remission of type 2 diabetes at 1 year after surgery.

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Baseline Predictors of Low-Density Lipoprotein Cholesterol and Systolic Blood Pressure Goal Attainment After 1 Year in the ISCHEMIA Trial

AHA Journal
Dec 10, 2019

In ISCHEMIA, older age, male sex, high-intensity statin use, lower baseline LDL-C, and North American location predicted 1-year LDL-C goal attainment

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Methylation Hotspots Evidenced by Deep Sequencing in Patients with Facioscapulohumeral Dystrophy and Mosaicism

AAN
Dec 10, 2019

Deep sequencing–based methylation analysis discriminates mosaic cases for which methylation changes have never been evaluated previously.

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Latitude Continues to be Significantly Associated with the Prevalence of Multiple Sclerosis

JNNP
Dec 09, 2019

This new meta-analysis confirms that MS prevalence is still strongly positively associated with increasing latitude and that the gradient is increasing.

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Immune Checkpoint Inhibitor Therapy in Patients With Preexisting Inflammatory Bowel Disease

J Clinical Oncology
Dec 09, 2019

Preexisting IBD increases the risk of severe GI adverse events in patients treated with immune checkpoint inhibitors.

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Increased Risk of Osteoporotic Fracture in Postgastrectomy Gastric Cancer Survivors

Am J Gastro.
Dec 06, 2019

Gastric cancer survivors who underwent gastrectomy had an increased osteoporotic fracture risk than did matched controls.

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Feasibility of Hepatitis B Vaccination by Microneedle Patch

J Infect Disease
Dec 06, 2019

dMNP delivery of AFV can elicit seroprotective anti-HBs levels in rhesus macaques that are correlated with human seroprotection

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