Efficacy and Safety of Fractional Microneedle Radiofrequency for Atrophic Acne Scars

Lasers Surg. Med.
Mar 19, 2024

FMR is a safe and effective treatment modality for improving facial atrophic acne scars, and the number of FMR treatment sessions and pulse width are associated with clinical efficacy.

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Single-Cell Transcriptomic Analysis Deciphers Heterogenous Cancer Stem-Like Cells in Colorectal Cancer and Their Organ-Specific Metastasis

Gut
Mar 18, 2024

By using integrative scRNA-seq, spatial transcriptomic analysis and functional assays, authors have uncovered a stem-like cell cluster marked with PTPRO and ASCL2 as the metastatic culprit, whose subpopulations show further different liver or ovary organotropism.

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Exploring the Interrelationships Between Physical Function, Functional Exercise Capacity, and Exercise Self-Efficacy in Persons Living with HIV

Clinical Nursing Research
Mar 12, 2024

While physical activity can mitigate the metabolic effects of HIV disease and HIV medications, many HIV-infected persons report low levels of physical activity.

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Telehealth Privacy and Security Tips

Skyscape
Mar 19, 2024

Buzz, a HIPAA-complaint platform enables providers to conduct secure video conferences or calls with patients quickly, easily & seamlessly.

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Childhood-Onset Myopathy With Preserved Ambulation Caused by a Recurrent ADSSL1 Missense Variant

Neuro Genetics
Mar 08, 2024

This study expands the phenotypic spectrum and variability of ADSSL1 myopathy with unusual manifestations in this rare disorder. Because the variant c.781G>A (p.Asp261Asn) is the most common mutation among Indian patients similar to other Asian cohorts, this finding could be useful for genetic screening of suspected patients.

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Transcatheter or Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis and Small Aortic Annulus

Circulation
Mar 07, 2024

In patients with severe aortic stenosis and SAA (women in the majority), there was no evidence of superiority of contemporary TAVR versus SAVR in valve hemodynamic results. After a median follow-up of 2 years, there were no differences in clinical outcomes between groups. These findings suggest that the 2 therapies represent a valid alternative for treating patients with severe aortic stenosis and SAA, and treatment selection should likely be individualized according to baseline characteristics, additional anatomical risk factors, and patient preference.

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Human Hair Graying Revisited

JID
Mar 06, 2024

The temporary reversibility of graying is highlighted by several drugs and hormones that induce repigmentation, indicating potential target pathways. Authors advise caution in directly applying mouse model concepts, define major open questions, and discuss future human antigraying strategies.

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Breastfeeding Characteristics and Duration of Feeding Human Milk in Infants With Congenital Heart Disease

JPNN
Mar 05, 2024

Future efforts to support feeding human milk in infants with CHD should emphasize practices that support maximal human milk production.

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Enhancing Functional Recovery Following Postpartum Femoral Neuropathy

Intl J Gynecol Obstet.
Mar 05, 2024

The case report describes how an early multimodal rehabilitation program within a multidisciplinary framework allows for sooner neuromotor function improvement and activities of daily living independence.

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Safety and Immunogenicity of Shorter Interval Schedules of the Novel Oral Poliovirus Vaccine Type 2 in Infants

The Lancet
Mar 04, 2024

Two nOPV2 doses administered 1 week or 2 weeks apart from age 6 weeks to 8 weeks were safe and immunogenic. Immune responses after a 2-week interval were non-inferior to those after the standard 4-week interval, but marked responses after a 1-week interval suggest that schedules with an over 1-week interval can be used to provide flexibility to campaigns to improve coverage and hasten protection during circulating vaccine-derived poliovirus type 2 outbreaks.

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Kidney Function, Albuminuria, and Risk of Incident Atrial Fibrillation

Am J Kidney Dis
Mar 01, 2024

Lower eGFR and greater albuminuria were independently associated with increased risk of incident AF. CKD should be regarded as an independent risk factor for incident AF.

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