NurseBeats

Impact of Individualized Versus Weight-Based Pain Protocols on Patient Satisfaction for Patients With Sickle Cell Disease Experiencing a Vaso-Occlusive Episode

The findings support evidence-based guidelines to manage vaso-occlusive episodes in emergency departments. Patient-specific protocols can be implemented by partnering with local sickle cell disease providers to make protocols available in the emergency department.

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Immunogenicity, Safety, and Efficacy of the Vaccine H56:IC31

Vaccination with H56:IC31 at treatment completion for pulmonary tuberculosis did not reduce the risk of recurrent disease. H56:IC31 was well tolerated and immunogenic but might have increased the risk of relapses by endogenous strains.

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Association of Nonmodifiable Risk Factors With Alzheimer Disease Blood Biomarkers in Community-Dwelling Adults in the ESTHER Study

This population-based study on dementia biomarkers found that P-tau181 was dependent on age and APOEe4; NfL on age and sex; and GFAP on age, sex, APOEe4, and menopause status. GFAP levels and rate of increase were higher in women, especially in premenopausal participants.

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Time to Start Minimal Enteral Nutrition in Low Birth Weight Infants and Its Predictors

As early of initiation of minimal enteral nutrition has a significant role to shorten the time to reach full enteral feeding and reducing malnutrition in the NICU health care staffs treating LBW neonates should consider nutrition as part of the management and special concerns should be given for those who are very preterm and very LBW. Experts in the area and hospitals should prepare feeding initiation protocol to be used across all hospitals and health care staffs to avoid a variation in time to MEN among different neonatal units.

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Medication Prescriptions for Chronic Diseases in Terminal Cancer Patients in Korea

These findings underscore the need to reevaluate prescription practices for terminal cancer patients. Optimizing medication use can decrease polypharmacy, reduce adverse drug reactions, and increase the quality of life (QOL) for these individuals.

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Fear of Disease Progression and Resilience Parallelly Mediated the Effect of Post-Stroke Fatigue on Post-Stroke Depression

An interprofessional effort to minimize patient interruptions at night in an intensive care unit setting led to improved patient sleep quality and sustainable practice changes.

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Distribution of Port-Wine Birthmarks and Glaucoma Outcomes in Sturge-Weber Syndrome

Lower eyelid and choroidal angiomas were associated with glaucoma diagnosis, suggesting a spatial relationship with SWS findings. However, leptomeningeal angiomas were not associated, possibly because these are further from the eye.

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A Pilot Randomized Control Trial of Holding During Hypothermia and Effects on Maternal and Infant Salivary Cortisol Levels

Authors demonstrate positive effects of holding during TH as evidenced by lower salivary cortisol for both mother and infant and decreased heart rate, respiratory rate, and blood pressure for the infant on day-2. Further research is needed to replicate these results, to understand the lack of infant response on day-3 and to assess correlation with cumulative morphine exposure.

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Impact of a Sleep-Promoting Schedule on Sleep Quality in the Intensive Care Unit

An interprofessional effort to minimize patient interruptions at night in an intensive care unit setting led to improved patient sleep quality and sustainable practice changes.

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Strong Association of Autoantibodies Targeting Deamidated Extracellular Epitopes of Insulinoma Antigen-2 With Clinical Onset of Type 1 Diabetes

CD4+ T cells from patients with type 1 diabetes (T1D) have a significant response to post-translationally modified (PTM) deamidated IA-2 peptides; autoantibodies to these PTM neoepitopes remain to be identified in T1D.

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